Parenteral – Injectable

 

Parenteral - Injectable

Injectable products require a unique formulation strategy. The formulated product must be sterile, pyrogen-free, and, in the case of solution, free of particulate matter. No coloring agent may be added solely for the purpose of coloring the parenteral preparation. The formulation should preferably be isotonic, and depending on the route of administration, certain excipients are not allowed. The injected drug by-passes natural defense barriers; hence, for any given drug, the risk of an adverse event may be greater or the effects difficult to reverse if administered as an injection rather than a non-parenteral route. For this reason ultra high purity grades of excipients are available for parenteral administration. Sterility requirements demand that an excipient is able to withstand terminal sterilization or aseptic processing.

Mutchler and our suppliers offer a variety of parenteral excipients despite the limiting factors above.

 

Below is a selection of our parenteral excipient offerings:

 

BASF parenteral excipients include

 

  • Kollidon 12 PF and Kollidon 17 PF
  • Kolliphor EL and Kolliphor EL-P
  • Kollisolv PYR
  • Kolliphor HS 15

 

Roquette Parenteral excipients include

 

  • Pearlitol PF
  • Neosorb PF
  • Lycadex PF
  • Kleptose HP and HPB parenteral grade